Our project pipeline
Our services include a project design and different phases of experimental procedures and analysis.
They are fully customizable and addapted to your project needs.
Organoid generation
Project design; choice choice of target cellular target cellular culture timelines (organoid maturation status). Generation of midbrain organoids.
Experimental analysis
Wet lab experiments based on the the project needs (neuronal phenotypes, autophagy, mitochondrial phenotypes, neuroinflammation, etc ).
Compound treatment
Project design; choice of drug concentrations and treatment duration. Treatment of midbrain organoids with drug candidates.
Data analysis
Complete analysis of the observed results accompanied by a discussion.
Image analysis and artifical intelligence
We use a set of computational AI tools to perform deep phenotyping of our models to better detect cellular defects and their rescue following compound treatments. Fore more details see our publication.
IP
Monzel A.S., Bolognin S., Schwamborn J.C. (2016) Means and methods for generating midbrain organoids. WO2017060884A1; PCT/IB2016/056054
